He led the Church for 14 years and died a martyrs death during the persecution of Decius in a.d. 250. St. Cyprian wrote to his successor that Fabian was an incomparable man whose glory in death matched the holiness and purity of his life.
In the catacombs of St. Callistus, the stone that covered Fabians grave may still be seen, broken into four pieces, bearing the Greek words, Fabian, bishop, martyr.