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As in the case of Agnes, another virgin-martyr of the early Church, almost nothing is historically certain about this saint except that she was martyred in Sicily during the persecution of Emperor Decius in 251.

Legend has it that Agatha, like Agnes, was arrested as a Christian, tortured and sent to a house of prostitution to be mistreated. She was preserved from being violated, and was later put to death.

She is claimed as the patroness of both Palermo and Catania. The year after her death, the stilling of an eruption of Mt. Etna was attributed to her intercession. As a result, apparently, people continued to ask her prayers for protection against fire.