DefinitionOrthostatic hypotension is a condition of abnormal blood pressure regulation upon standing. The blood pressure quickly decreases, more than 20/10 mm Hg, when rising from a lying down or sitting position to a standing position.
|Measuring of Blood Pressure|
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CausesOrthostatic hypotension has several causes.
- Hypovolemia is the most common cause. It may be due to:
- Impaired autonomic (nerve) reflex due to certain diseases:
- Decreased heart muscle contractility or vascular responsiveness
- Certain drugs:
- Monoamine oxidase (MAO) inhibitors
- Tricyclic antidepressants
- Tetracyclic antidepressants
- Phenothiazine antipsychotic drugs, such as chlorpromazine, promazine, thioridazine
- Atypical antipsychotics
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