DefinitionWhipple’s disease is a rare infectious disease.
CausesWhipple’s disease is caused by a specific type of bacteria. It causes abnormal changes on the wall of the small intestine. These changes disrupt the villi. Villi are tiny, finger-like structures that stick out from the wall of the intestine to help absorb nutrients. As a result, some nutrients are not absorbed properly and do not reach the rest of the body.
|Cross Section of Intestine With Villi|
|Copyright © Nucleus Medical Media, Inc.|
Risk FactorsThere is no evidence that Whipple’s disease is passed from person to person. But, there is some evidence that the bacteria may be present in people who are healthy. This suggests that the few people who develop the disease may have an abnormal response to the bacteria. Some people with Whipple’s disease may have a genetic defect that makes them more likely to develop the disease. Whipple’s disease occurs mainly in middle-aged men.
SymptomsThis disease can affect many parts of the body. The small intestine is the main organ affected. Symptoms usually begin slowly and occur in stages. The first stage includes:
- Pain in the joints (in 90% of cases)
- Pain and bloating in the abdomen
- Fatty foul-smelling stools
- Bleeding from the intestines
- Weight loss
- Fatigue (often from anemia )
- Cough and chest pain
- Increased skin pigmentation (in 50% of cases)
- Swollen lymph glands
More from Beliefnet
A randomized trial found that fecal microbiota transplantation had a higher rate of remission in patients with active ulcerative colitis than those who recieved placebo. Fecal transplantation is believed to help the intestine develop a healthy balance of bacteria in the gut which can help the intestine recover and function more effectively.
Exercise Associated with Healthy Baby Weight
Mindful Meditation May Reduce Symptoms and Complications of Insomnia
Chewing Gum After Surgery May Improve Digestive Tract Recovery