Tramadol

Trade Names :

  • Ultram

Tramadol is a unique non-narcotic and non-anti-inflammatory analgesic medication used for the treatment of moderate pain. It has many effects in the body, including some that relate to endorphins and others that involve serotonin. 

St. John's Wort5-HTP (5-Hydroxytryptophan)SAMe (S-Adenosylmethionine) There are two case reports that possibly implicate tramadol in serotonin syndrome. 1,2 This syndrome is caused by excessive levels of serotonin, which bring about various dangerous side effects. Since St. John's wort and 5-HTP might increase serotonin levels, and SAMe (S-adenosylmethionine) has reportedly caused serotonin syndrome, combining any of them with tramadol could be risky.

References

1
Mason BJ and Blackburn KH. Possible serotonin syndrome associated with tramadol and sertraline coadministration. Ann Pharmacother 31: 175–177, 1997.

2
Hernandez AF, et al. Fatal moclobemide overdose or death caused by serotonin syndrome? J Forensic Sci 40: 128–130, 1995.

Revision Information

leave comments
0
Did you like this? Share with your family and friends.
Related Topics: Health And Healing
Meet Our Health Experts
Simply Fabulous

Simply Fabulous

Jennifer Baxter
New! Faith Like a Child
beginners heart

Beginner's Heart

Britton Gildersleeve
New! a surefire cure for the blues

Our Lady of Weight Loss

Janice Taylor
New! Take a Bach Break. Lose Weight... Sometimes its just that simple


Advertisement

Our Free Newsletter
click here to see all of our uplifting newsletters »

 

Advertisement

DiggDeliciousNewsvineRedditStumbleTechnoratiFacebook