Alternate Names

  • Digitoxin

Trade Names

  • Crystodigin
  • Lanoxicaps
  • Lanoxin

Magnesium - Supplementation Possibly Helpful, but Take at a Different Time of Day Calcium - Supplementation Possibly Helpful Hawthorn - Possible Interaction Licorice - Possible Dangerous Interaction Eleutherococcus senticosus - Possible Interaction Horsetail - Possible Dangerous Interaction St. John's Wort - Possible Reduction of Effectiveness of Drug Uzara - Possible Harmful Effect Gingko biloba - No Interaction

The digitalis drugs digoxin and digitoxin are used for congestive heart failure and other heart conditions. The concerns described below apply equally to both medications.

Magnesium Magnesium deficiency can increase the risk of toxicity from digoxin. 12 However, taking magnesium supplements at the same time as digoxin might impair the absorption of the drug. 5 The solution? Do not take your magnesium supplement during the two hours before or after your digoxin dose.

Calcium Although the evidence is quite weak, digoxin might cause a tendency toward calcium deficiency. 6 Taking calcium supplements could not hurt.

Hawthorn The herb hawthorn is used to treat congestive heart failure. Whether it is safe to combine hawthorn with digoxin remains unclear. One small study failed to find any harmful interaction, but more research must be done before reliable conclusions can be drawn. 16 .

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