Trade Names :
Nitroglycerin (NTG) is one of the most commonly used treatments for quick relief of anginal pain. Related drugs include isosorbide dinitrate and isosorbide mononitrate.
N-Acetyl Cysteine (NAC)N-acetyl cysteine (NAC) is a specially modified form of the dietary amino acid cysteine that has various proposed uses. Nitrates such as nitroglycerin lose some of their effectiveness over time. According to some studies, 1,2 but not all, 3,4 the supplement N-acetyl cysteine might help these drugs work better. However, there's a catch: the combination of NAC and nitroglycerin appears to cause severe headaches. 5,6Taking NAC with nitroglycerin may be beneficial in some cases. However, unpleasant side effects probably limit the use of this combination.Note: Angina is too serious a disease for self-treatment. If you have angina, do not take any supplement except on a physician’s advice.
Vitamin C Vitamin C may help prevent the development of tolerance to nitrate medications such as nitroglycerin. According to a double-blind study of 48 individuals, use of vitamin C at a dose of 2000 mg three times daily helped maintain the effectiveness of nitroglycerin. 10 These findings are supported by other studies as well. 9,13,14Note: Angina is too serious a disease for self-treatment. If you have angina, do not take any supplement except on a physician’s advice.