(Basal Cell Carcinoma; Squamous Cell Carcinoma)
DefinitionSkin cancer is when cancer cells grow in the skin.The two most common kinds of skin cancer are:
- Basal cell carcinoma —Basal cell carcinoma is the most common form of skin cancer. This cancer usually grows slowly and rarely spreads to other tissues in the body.Basal cell carcinoma is rarely fatal but it can cause damage to the nearby tissue. If there is risk of damage, the cancer may need treatment or removal.
- Squamous cell carcinoma —Squamous cell carcinoma is the second most common form of skin cancer.The cancer develops in the uppermost layer of skin cells. Squamous cell carcinoma usually grows slowly. It is rarely fatal if treated early. However, the cancer can be lethal if it spreads beyond the skin.
|Basal Cell Carcinoma|
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CausesCancer occurs when skin cells in the body divide without control or order. When cells keep dividing uncontrollably when new cells are not needed, a mass of tissue forms. This is called a growth or tumor. Unlike benign tumors, malignant tumors can invade nearby tissues and spread to other parts of the body.
Risk FactorsBasal and squamous cell cancers are more common in men and in people over 50 years old. These cancers are most likely to occur in people with:
- Fair skin that freckles easily
- Red or blonde hair
- Light-colored eyes
- Caucasian skin
- Personal history of skin cancer
- Exposure to ultraviolet radiation from the sun or artificial radiation from a tanning bed
- Excessive sun exposure without protective clothing or sunscreen
- Skin damage from burns or infections
- Exposure to arsenic, industrial tar, coal, paraffin, and certain types of oil
- Radiation therapy treatment
- Light treatments for psoriasis , especially psoralen ultraviolet A (PUVA)
- Having a weak immune system due to illness or medications
- Certain genetic diseases, such as basal cell nevus syndrome or xeroderma pigmentosum
SymptomsMost skin cancers do not cause symptoms. The most common first symptom of skin cancer is a change in the skin.Basal cell carcinoma may appear as a:
- Slowly expanding, painless growth
- Bleeding scab or sore that heals and recurs
- Flat, firm, pale area
- Small, raised, pink, red, shy, or pearly areas thay may bleed easily
- Large oozing, crusted area
- Growing lumps with rough, scaly, or crusted surfaces
- Slow-growing flat, reddish patches in the skin
- Recurrent, nonhealing ulceration or bleeding
DiagnosisYou will be asked about your symptoms and medical history. A physical exam will be done. You may have a biopsy . The sample can then be examined for cancer cells. In cases where the growth is large, or has been present for a long time, the lymph nodes in the area will be checked. More tests may be advised to determine if the cancer has spread to other parts of the body.
TreatmentTalk to your doctor about the best treatment for you. Treatment may include one or more of the following:
SurgeryMany skin cancers can be cut from the skin quickly and easily. In fact, the cancer is sometimes completely removed during biopsy and no further treatment is needed. Surgical techniques include:Simple ExcisionA surgical knife is used to cut out the lesion . Curettage and ElectrodesiccationThis involves scooping the cancer out with a curette, an instrument with a sharp, spoon-shaped end. The area is treated with an electric current to control bleeding. This also kills any cancer cells remaining around the edge of the wound. This technique is used for small or superficial cancers.Mohs SurgeryMohs surgery is the removal of all of the cancerous tissue. The surgeon will try to remove as little healthy tissue as possible. This method is used to remove:
- Large tumors
- Tumors in hard-to-treat places
- Tumors of undetermined shape and depth
- Cancers that have recurred
Laser TherapyLaser therapy uses a narrow beam of light to remove or destroy cancer cells. This method is sometimes used for cancers in the outer layer of skin.
Radiation TherapyRadiation therapy uses radiation to kill cancer cells and shrink tumors.
Topical ChemotherapyTopical chemotherapy is the use of drugs to kill cancer cells. The drugs can be creams or lotions. This method is successful in treating precancerous conditions and cancers limited to the outer layer of the skin. The most common topical chemotherapy used is a form of 5-fluorouracil (5-FU) .
ImmunotherapyMedications such as imiquimod increase your body's own reponse to fight the cancer cells.
PreventionTo prevent skin cancer:
- Avoid spending too much time in the sun.
- Avoid exposing your skin to the sun between 10:00 AM and 2:00 PM standard time, or 11:00 AM to 3:00 PM daylight saving time.
- Protect your skin from the sun with clothing. Wear a shirt, sunglasses, and a hat with a broad brim.
- Use broad-spectrum (UVA and UVB) sunscreens with a sun protection factor (SPF) of 30 or more on skin that will be exposed to the sun.
- Use a protective lip balm.
- Wear sunglasses with 99% or 100% UV absorption to protect your eyes.
- Don't use sun lamps or tanning booths.
- If you have any of the symptoms listed above, have your skin examined by a doctor.
- If you have fair skin, have your skin checked by a doctor.
- Learn how to do a skin self-exam .
American Academy of Dermatology
American Cancer Society
Canadian Cancer Society
Canadian Dermatology Association
Alberta Provincial Cutaneous Tumour Team. Prevention of skin cancer. Edmonton (Alberta): CancerControl Alberta; 2013 Feb. 27 p. (Clinical practice guideline; no. CU-014). Available at: http://www.guideline.gov/content.aspx?id=48130#Section420. Accessed February 25, 2015.
Basal cell carcinoma of the skin. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated December 18, 2014. Accessed February 25, 2015.
Skin cancer: basal and squamous cell. American Cancer Society website. Available at: http://www.cancer.org/acs/groups/cid/documents/webcontent/003139-pdf.pdf. Updated February 20, 2014. Accessed February 25, 2015.
Skin cancer. National Cancer Institute website. Available at: http://www.cancer.gov/cancertopics/types/skin. Accessed February 25, 2015.
Squamous cell carcinoma. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated January 16, 2015. Accessed February 25, 2015.
Sunscreen FAQs. American Academy of Dermatology website. Available at: https://www.aad.org/media-resources/stats-and-facts/prevention-and-care/sunscreens. Accessed February 25, 2015.
- Reviewer: Mohei Abouzied, MD
- Review Date: 02/2015
- Update Date: 10/20/2014
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