Gangrene

(Dry Gangrene; Gas Gangrene; Organ or Tissue Death; Wet Gangrene)

Definition

Gangrene is the progressive death of body tissue resulting from a lack of blood supply. When the blood supply is cut off, the tissue does not get enough oxygen and begins to die.Gangrene can be internal or external. The two most common types of gangrene are:
  • Dry gangrene—Lack of blood supply causes the tissue to die.
  • Wet gangrene—Usually occurs when the tissue is infected with bacteria from an injury. The tissue becomes moist and breaks down.
A rare wet type, called gas gangrene, develops from specific bacteria deep inside the body. Gas gangrene can be a result of surgery or trauma.

Causes

Gangrene is caused by infection or a reduced blood supply to tissues.

Risk Factors

Gangrene is more common in older adults. Factors that may increase your chance of developing gangrene include:

Symptoms

External gangrene may cause:
  • Color changes, ranging from white, to red, to black
  • Shiny appearance to skin
  • Foul-smelling, frothy, clear, or watery discharge
  • Shedding off of skin
  • Severe pain followed by loss of feeling in the affected area
Internal gangrene may cause:
  • Fever and chills
  • Confusion
  • Nausea and vomiting
  • Diarrhea
  • Lightheadedness or fainting, which may be caused by low blood pressure
If the gangrene is widespread, sepsis can occur.
Gangrene of the Foot
nucleus factsheet image
Copyright © Nucleus Medical Media, Inc.

Diagnosis

You will be asked about your symptoms and medical history. A physical exam will be done.Your bodily fluids may be tested. This can be done with: :
  • Blood tests
  • Tests of the discharge and the tissue
Images may be taken of your bodily structures. This can be done with:

Treatment

Treatment of gangrene includes:
  • IV antibiotics—to treat infection
  • Debridement —surgical procedure to cut away dead and dying tissue, done to try to avoid gangrene from spreading
  • Supportive care, including fluids, nutrients, and pain medication to relieve discomfort
  • Blood thinners—given to prevent blood clots
  • Surgery may also be done to restore blood flow to the affected area
  • Amputation—removal of severely affected body part
  • Hyperbaric oxygen treatment—exposing the affected tissue to oxygen at high pressure may have some benefit

Advertisement

Prevention

To help reduce your chance of getting gangrene, take these steps:
  • If you have chronic health conditions, follow the treatment plan outlined by your doctor.
  • If you have diabetes, inspect your feet every day for cuts, sores, or wounds.
  • Care for any cuts, sores, or wounds promptly to avoid infection.
  • If you need surgery, ask your doctor about taking antibiotics. This is especially true if you need intestinal surgery.

RESOURCES

American Diabetes Association
http://www.diabetes.org

Family Doctor—American Academy of Family Physicians
http://www.familydoctor.org

CANADIAN RESOURCES

Canadian Diabetes Association
http://www.diabetes.ca

Health Canada
http://www.hc-sc.gc.ca

References

A quick summary of the 6 types of necrosis. Pathology Student website. Available at: http://www.pathologystudent.com/?p=5770. Accessed September 29, 2014.

Fujiwara Y, Kishida K, et al. Beneficial effects of foot care nursing for people with diabetes mellitus: an uncontrolled before and after intervention study.J Adv Nurs. 2011;67(9):1952-1962.

Gangrene. NHS Choices website. Available at: http://www.nhs.uk/Conditions/Gangrene/Pages/Introduction.aspx. Accessed January 27, 2014.

Gas gangrene. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated July 25, 2014. Accessed September 29, 2014.

Sepsis in adults. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated July 25, 2014. Accessed September 29, 2014.

Revision Information

leave comments
0
Did you like this? Share with your family and friends.
Related Topics:
Current Research From Top Journals


Early Peanut Consumption Associated with Lower Risk of Peanut Allergy in High Risk Children
March 2015

Many medical groups felt that early exposure to certain foods like peanuts increased a child's risk of developing food allergies. However, newer research including this trial suggest that early exposure may actually decrease the risk of developing food allergies.

dot separator
previous editions

Breastfeeding May Decrease the Risk of Childhood Obesity
February 2015

Tonsillectomy May Reduce Number of Sore Throat Days in Children
February 2015

Research Review Finds Little Support for Nearly Half of Medical Talk Show Recommendations
January 2015

dashed separator

Advertisement

Our Free Newsletter
click here to see all of our uplifting newsletters »

 

Advertisement

Advertisement

DiggDeliciousNewsvineRedditStumbleTechnoratiFacebook