Paget's Disease

(Osteitis Deformans)

Definition

Paget's disease is a bone condition that results in enlarged and deformed bones. It is a long-term condition. Any bone in the body can be affected. However, the most common sites are the spine, skull, pelvis, thighs, and lower legs.
Normal Bone Structure
Bone Matrix
Copyright © Nucleus Medical Media, Inc.

Causes

Paget's disease is caused by a malfunction in bone formation. Normally, bones are constantly being broken down and rebuilt. With Paget's disease, bones are broken down abnormally fast, and new bone replacement is loose and bulky, instead of strong and compact. These poorly formed bones may become weak. They also may bend over time.The exact cause of this bone malformation is unknown. Paget's disease may be triggered early in life by a viral infection.

Risk Factors

Paget's disease is more common in people who:
  • Have a family history, especially in a parent, sibling, or child
  • Are of Northern European decent
  • Are aged 55 years or older
  • Smoke

Symptoms

Most people with Paget's disease don't have symptoms. For those with symptoms, Paget's disease may cause:
  • Chronic bone pain, especially legs, hips, or spine
  • Swelling or deformity of a limb
  • Broken bones
  • Bowing of a limb
  • Damaged cartilage in the joints
Paget's disease that involves the skull may cause:
  • Increased head size
  • Headaches
  • Facial pain
  • Hearing loss
Paget's disease doesn't spread to other bones, but the symptoms do get worse over time.

Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done. Your doctor will order a blood test.Imaging tests take pictures of internal body structures. These are done with:

leave comments
0
Did you like this? Share with your family and friends.
Related Topics:
Current Research From Top Journals


Early Peanut Consumption Associated with Lower Risk of Peanut Allergy in High Risk Children
March 2015

Many medical groups felt that early exposure to certain foods like peanuts increased a child's risk of developing food allergies. However, newer research including this trial suggest that early exposure may actually decrease the risk of developing food allergies.

dot separator
previous editions

Breastfeeding May Decrease the Risk of Childhood Obesity
February 2015

Tonsillectomy May Reduce Number of Sore Throat Days in Children
February 2015

Research Review Finds Little Support for Nearly Half of Medical Talk Show Recommendations
January 2015

dashed separator

Advertisement

Our Free Newsletter
click here to see all of our uplifting newsletters »

 

Advertisement

Advertisement

DiggDeliciousNewsvineRedditStumbleTechnoratiFacebook