Schizophrenia is a chronic, severe, disabling brain disorder. It interferes with the way a person interprets reality. People with schizophrenia may:
  • Hear voices or see things that others do not
  • Become paranoid that people are plotting against them
  • Experience cognitive deficits
  • Withdraw socially
These and other symptoms make it difficult for people with schizophrenia to have positive relationships with others.
Regions of the Brain
Colored brain segments
Schizophrenia affects many different areas of the brain causing a wide range of behavioral, emotional, and intellectual symptoms.
Copyright © Nucleus Medical Media, Inc.


The cause of schizophrenia is unknown but it is associated with problems in brain structure and chemistry. There may be some genetic role.Schizophrenia does not develop because of one factor. You may have a gene that increases your chance of schizophrenia, but you may not develop the disease based on your environment. Environment means any outside factor like stress or infection.

Risk Factors

Factors that may increase your chance of schizophrenia include:
  • Having a parent or sibling with schizophrenia
  • Marijuana use or other drug use
  • Father being of older age
  • Other factors, like problems during pregnancy or birth such as infection


Men typically develop symptoms in their late teens or early twenties. Schizophrenia in women tends to occur in their twenties or thirties. In rare cases, it is seen in childhood.Symptoms often appear slowly. They may become more disturbing and bizarre over time or occur in a matter of weeks or months.Symptoms may include:
  • Hallucinations—seeing or hearing things/voices that are not there
  • Delusions—strong but false personal beliefs that are not based in reality
  • Disorganized thinking
  • Disorganized speech—lack of ability to speak in a way that makes sense
  • Catatonic behavior—slow movement, repeating rhythmic gestures, pacing, walking in circles, refusal to do things, repetitive speech
  • Emotional flatness—flat speech, lack of facial expression, and general disinterest and withdrawal
  • Paranoia
  • Inappropriate laughter
  • Poor hygiene and self-care

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