Born into a prosperous, devout family in Guadalupe de Zacatecas, he entered the Jesuits in 1911 but three years later fled to Granada, Spain, because of religious persecution in Mexico. He was ordained in Belgium in 1925.
He immediately returned to Mexico, where he served a Church forced to go underground. He celebrated the Eucharist clandestinely and ministered the other sacraments to small groups of Catholics.
He and his brother Roberto were arrested on trumped-up charges of attempting to assassinate Mexicos president. Roberto was spared but Miguel was sentenced to face a firing squad on November 23, 1927. His funeral became a public demonstration of faith. He was beatified in 1988.