Famous comedian and television host Ellen experienced a depression onset by extreme life events. In 1997 she came out publicly as a lesbian. The media blitz that followed left her in a dark depression for nearly three years. It led in part to the cancellation of her sitcom Ellen, and mired her relationship with then-partner Anne Heche. It is clear that Ellen has overcome those dark days, as her current talk show is a huge hit and she is as upbeat as she has ever been, even with her extremely sarcastic tone.