{"id":10485,"date":"2018-11-12T08:00:41","date_gmt":"2018-11-12T13:00:41","guid":{"rendered":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/?p=10485"},"modified":"2018-11-26T05:47:41","modified_gmt":"2018-11-26T10:47:41","slug":"new-treatment-resistant-depression","status":"publish","type":"post","link":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/2018\/11\/new-treatment-resistant-depression.html","title":{"rendered":"New Treatment for Resistant Depression"},"content":{"rendered":"<p><img decoding=\"async\" class=\"alignleft size-medium wp-image-10493\" src=\"https:\/\/wp-media.beliefnet.com\/sites\/258\/2018\/11\/disappointed-2167435_1920-200x300.jpg\" alt=\"disappointed-2167435_1920\" width=\"200\" height=\"300\" \/>Jack has suffered with depression for years. He is one of 5 million people who have what is called treatment-resistant depression. He has tried numerous antidepressant drugs that would work for a while and then seem to stop working. Recently, he joined a clinical trial using a drug that most people know as a psychedelic one-ketamine. Ketamine has been used by anesthesiologist to put people under before surgery, but it is widely known as &#8220;Special K,&#8221; a hallucinogen used by club goers to trip. It is an easy drug to abuse.<\/p>\n<p>Now, the drug is being studied to bring possible hope to those suffering from stubborn depression. And because ketamine is legally prescribed for anesthesia, it has been used off label as a possible new treatment. Currently the trials are small and few, but the early results seem promising.<\/p>\n<p>The drug is not yet FDA approved for depression but it appears that the response from those with treatment-resistant depression is hopeful. Patients report that it seems to help with suicidal thoughts and has rapid results.<\/p>\n<p>How ketamine exactly works to fight resistant\u00a0depression is not exactly known, but it seems to work rapidly in the brain. Because it has not been largely studied as a depression treatment, we don&#8217;t know the consequences and potential side effect of using this repeatedly\u00a0for depression. With anesthesia, one dose is given. As a depression treatment, doses are\u00a0repeated because the effects are temporary. And the drug is costly ($400-$800 a treatment) and rarely covered by insurance.<\/p>\n<p>Also, because it is a drug of abuse, people can become dependents on it. Furthermore, it has been correlated with bladder toxicity and cognitive problems in the recreational drug crowd.<\/p>\n<p>A task force of the American Psychiatric Association has said that ketamine is not ready for a roll out to the public. It needs more study despite the fact that private clinics have popped up all over the country and are providing this treatment. A big concern is that this treatment may not be a long-term solution and may stimulate opioid receptors in the brain. This could then\u00a0bring on the problem of potential addiction like we currently see with opioids.<\/p>\n<p>That said, researchers are working on how the drug works, how to dose it and use it as an antidepressant so as to not provide the euphoric effect. So, stay tuned on this one. As clinical trials continue, we may see a new treatment for hard to treat depression. More research will be telling.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jack has suffered with depression for years. He is one of 5 million people who have what is called treatment-resistant depression. He has tried numerous antidepressant drugs that would work for a while and then seem to stop working. Recently, he joined a clinical trial using a drug that most people know as a psychedelic&hellip;<\/p>\n","protected":false},"author":419,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4100],"tags":[304,4313,4311,4314,4312],"class_list":["post-10485","post","type-post","status-publish","format-standard","hentry","category-health","tag-depression","tag-ketamine","tag-resistent-depression","tag-special-k","tag-stubbord-depression"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New Treatment for Resistant Depression<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/2018\/11\/new-treatment-resistant-depression.html\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Treatment for Resistant Depression\" \/>\n<meta property=\"og:description\" content=\"Jack has suffered with depression for years. He is one of 5 million people who have what is called treatment-resistant depression. He has tried numerous antidepressant drugs that would work for a while and then seem to stop working. Recently, he joined a clinical trial using a drug that most people know as a psychedelic&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/2018\/11\/new-treatment-resistant-depression.html\" \/>\n<meta property=\"og:site_name\" content=\"Doing Life Together\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/drlindamintle\/\" \/>\n<meta property=\"article:published_time\" content=\"2018-11-12T13:00:41+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-11-26T10:47:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/files\/2018\/11\/disappointed-2167435_1920-200x300.jpg\" \/>\n<meta name=\"author\" content=\"Linda Mintle\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@drlindamintle\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New Treatment for Resistant Depression","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/2018\/11\/new-treatment-resistant-depression.html","og_locale":"en_US","og_type":"article","og_title":"New Treatment for Resistant Depression","og_description":"Jack has suffered with depression for years. He is one of 5 million people who have what is called treatment-resistant depression. He has tried numerous antidepressant drugs that would work for a while and then seem to stop working. 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Dr. Linda\u2019s fun personality and expertise comes through whether she\u2019s helping her audience stress less or make peace with their thighs! Dr. Linda has her Ph.D. in Urban Health and Clinical Psychology and is a national expert on mental health. She has specialized in the treatment of eating disorders, anxiety, depression and pain management. With 30 years of clinical experience working with couples, families and individuals, she brings her common-sense approach to people who want to live in positive mental health. Dr. Linda is also a bestselling author with 21 book titles to her credit, a radio host of the Dr. Linda Mintle show, professor, national speaker, winner of the Mom\u2019s Choice Award, a national news consultant, featured writer for Beliefnet and hosts her own website. Her academic appointments keep her abreast of current research in her areas of expertise. Her media experience includes seven years as the resident expert for ABC Family\u2019s Living the Life television show and regular appearances on network television and radio. It is often said that being with Dr. Linda is like having coffee with a friend. She makes the complicated issues of relationships and mental health easy to understand and applicable to everyday living. The ease she has with people, coupled with her clinical training and experience makes her a sought-after speaker on college campuses, conferences and special events. Whether she is doing a TV skit with Tim Conway or discussing teen violence with Queen Latifa, Dr. Linda will entertain, educate and integrate faith and mental health in everyday living. Check out her latest book Hope and Healing for Anxiety, a whole-person approach to eliminate anxiety. .","sameAs":["https:\/\/drlindamintle.com\/","https:\/\/www.facebook.com\/drlindamintle\/","https:\/\/www.instagram.com\/drlindamintle\/","https:\/\/x.com\/drlindamintle"],"url":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/author\/lmintle"}]}},"_links":{"self":[{"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/posts\/10485","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/users\/419"}],"replies":[{"embeddable":true,"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/comments?post=10485"}],"version-history":[{"count":7,"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/posts\/10485\/revisions"}],"predecessor-version":[{"id":10528,"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/posts\/10485\/revisions\/10528"}],"wp:attachment":[{"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/media?parent=10485"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/categories?post=10485"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.beliefnet.com\/columnists\/doinglifetogether\/wp-json\/wp\/v2\/tags?post=10485"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}