{"id":4143,"date":"2024-02-09T09:35:10","date_gmt":"2024-02-09T14:35:10","guid":{"rendered":"https:\/\/www.beliefnet.com\/columnists\/dailycupofwellness\/?p=4143"},"modified":"2024-02-09T09:35:10","modified_gmt":"2024-02-09T14:35:10","slug":"how-rishi-sunaks-fasting-style-may-protect-against-parkinsons-and-alzheimers","status":"publish","type":"post","link":"https:\/\/www.beliefnet.com\/columnists\/dailycupofwellness\/2024\/02\/how-rishi-sunaks-fasting-style-may-protect-against-parkinsons-and-alzheimers.html","title":{"rendered":"How Rishi Sunak&#8217;s Fasting Style May Protect Against Parkinson&#8217;s and Alzheimer&#8217;s"},"content":{"rendered":"<figure id=\"attachment_4155\" aria-describedby=\"caption-attachment-4155\" style=\"width: 1200px\" class=\"wp-caption alignnone\"><img decoding=\"async\" class=\"size-full wp-image-4155\" src=\"https:\/\/wp-media.beliefnet.com\/sites\/410\/2024\/02\/intermittient-fasting-alzheimers-credit-marcin-malicki-shutterstock.jpg\" alt=\"intermittient fasting\" width=\"1200\" height=\"900\" \/><figcaption id=\"caption-attachment-4155\" class=\"wp-caption-text\">Marcin Malicki\/Shutterstock.com<\/figcaption><\/figure>\n<p>Cambridge scientists may have found a new way in which fasting helps reduce inflammation, a potentially damaging side effect of the body\u2019s immune system that underlines several chronic diseases like Parkinson\u2019s and Alzheimer\u2019s. Fasting increases levels of a chemical in the blood known as arachidonic acid, which inhibits inflammation. The researchers believe it may also help explain some of the beneficial effects of drugs like aspirin.<\/p>\n<p>For some time, scientists have known that our diet, particularly a high-calorie Western diet, can increase our risk of diseases, including heart disease, type 2 diabetes, and obesity, which are linked to chronic inflammation in the body. Inflammation is our body\u2019s natural response to injury or infection, but this process can be triggered by other mechanisms, including the so-called \u201cinflammasome,\u201d which acts like an alarm within our body\u2019s cells, triggering inflammation to help protect our body when it senses damage.<\/p>\n<p>However, the inflammasome can trigger inflammation in unintentional ways: one of its functions is to destroy unwanted cells, which can result in the release of the cell\u2019s contents into the body, where they trigger inflammation. Professor Clare Bryant from the Department of Medicine at the University of Cambridge said, \u201cWe\u2019re very interested in trying to understand the causes of chronic inflammation in the context of many human diseases, and in particular, the role of the inflammasome. What\u2019s become apparent over recent years is that one inflammasome in particular \u2013 the NLRP3 inflammasome \u2013 is very important in a number of major diseases such as obesity and atherosclerosis, but also in diseases like Alzheimer\u2019s and Parkinson\u2019s disease, many of the diseases of older age people, particularly in the Western world.\u201d<\/p>\n<p><iframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/OxEFhqAGnjg?si=sFWBM4E6WuUmIVKu\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>It follows the UK Prime Minister saying that<a href=\"https:\/\/inews.co.uk\/inews-lifestyle\/like-rishi-sunak-i-fast-for-36-hours-then-indulge-for-6-days-2879323?ico=in-line_link\">\u00a0fasting once a week was an \u201cimportant discipline\u201d for him<\/a> as part of a \u201cbalanced lifestyle.\u201d Rishi Sunak doesn&#8217;t eat anything for 36 hours at the start of each week, the <em>Sunday Times\u00a0<\/em>reported. Fasting can help reduce inflammation, but the reason why has not been clear. Scientists at the University of Cambridge and the National Institute for Health in the USA, therefore, studied blood samples from a group of 21 volunteers who ate a 500kcal meal and then fasted for 24 hours before consuming a second 500kcal meal. The team found\u00a0that restricting calorie intake increased levels of a lipid known as arachidonic acid.<\/p>\n<p>Lipids are molecules that play essential roles in our bodies, such as storing energy and transmitting information between cells. As soon as individuals ate a meal again, levels of arachidonic acid dropped. When the researchers studied arachidonic acid\u2019s effect on immune cells cultured in the lab, they found that it turned down the activity of the NLRP3 inflammasome. This came as a surprise as arachidonic acid was previously thought to be linked with increased levels of inflammation, not decreased.<\/p>\n<p>Professor Bryant, a fellow of Queens\u2019 College, Cambridge, said, \u201cThis provides a potential explanation for how changing our\u00a0diet\u00a0\u2013 in particular by fasting\u00a0\u2013 protects us from inflammation, especially the damaging form that underpins many diseases related to a Western high-calorie diet. It\u2019s too early to say whether fasting protects against diseases like Alzheimer\u2019s and Parkinson\u2019s disease, as the effects of arachidonic acid are only short-lived,<\/p>\n<p>She continued, \u201cBut our work adds to a growing amount of scientific literature that points to the health benefits of calorie restriction. It suggests that regular fasting over a long period could help reduce the chronic inflammation we associate with these conditions. It\u2019s certainly an attractive idea.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cambridge scientists may have found a new way in which fasting helps reduce inflammation, a potentially damaging side effect of the body\u2019s immune system that underlines several chronic diseases like Parkinson\u2019s and Alzheimer\u2019s. Fasting increases levels of a chemical in the blood known as arachidonic acid, which inhibits inflammation. The researchers believe it may also&hellip;<\/p>\n","protected":false},"author":657,"featured_media":4155,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fbia_status":"","footnotes":""},"categories":[173,40],"tags":[468,234,725],"class_list":["post-4143","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diet-habits","category-physical-health","tag-alzheimers","tag-fasting-diet","tag-parkinsons-disease"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How Rishi Sunak&#039;s Fasting Style May Protect Against Parkinson&#039;s and Alzheimer&#039;s<\/title>\n<meta name=\"description\" content=\"Cambridge scientists may have found a new way in which fasting helps reduce inflammation, a potentially damaging side effect of the body\u2019s immune system.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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