Invoke the Mayo Clinic on Melanoma! It is the most serious form of skin cancer and can kill you. According to the Mayo Clinic, exposure to ultraviolet (UV) radiation from sunlight or tanning lamps and beds increases your risk of developing melanoma. Melanoma in is increasing in females in your age group (15-29) more so than males thanks to the pressure from media. And indoor tanning increases the risk of melanoma by 75%.