Non-Hodgkin Lymphoma—Child

(Lymphoma, Non-Hodgkin—Child)

Definition

Lymphomas are cancers of the lymphatic system. This system drains excess fluid from the tissue. It also helps protect against infections. Non-Hodgkin lymphoma is a general name that applies to many types of lymphomas, which are based on:
  • The type of cell that is involved
  • The patterns of growth
In general, there are 2 main groups:
  • Slow growing lymphomas
  • Aggressive lymphomas
These cancers are different from Hodgkin lymphoma . This is another type of cancer that affects the lymphatic system.
The Lymphatic System
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Causes

The exact cause is not known. Mutations in genes may be related to this cancer.

Risk Factors

Some risk factors include:
  • History of chemotherapy and radiation therapy
  • Infections involving the immune system, such as HIV/AIDS or Epstein-Barr virus
  • Chronic hepatitis C infection
  • Genetic conditions, such as ataxia telangiectasia, X-linked lymphoproliferative disease, or Wiskott-Aldrich syndrome
  • A parent with non-Hodgkin lymphoma, especially if they had it at an early age

Symptoms

Symptoms may vary greatly in each child. Symptoms may include:
  • Painless swelling of the neck, underarm, groin, or any other lymph node area
  • Unexplained fever
  • Sore throat
  • Infections
  • Sweating
  • Constant fatigue
  • Unexplained weight loss
  • Itchy skin, especially on the legs and feet
  • Bone and joint pain
  • Chest pain or shortness of breath

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