Ewing's Sarcoma

(Peripheral Primitive Neuroectodermal Tumors [PNET]; Ewing's Family of Tumors)

Definition

Ewing's sarcoma is a cancerous bone tumor that may occur in any bone in the body. When it occurs in soft tissue, it is called extraosseous sarcoma. The most commonly affected areas include the pelvis, thigh, lower leg, upper arm, and chest wall.
Leg and Pelvic Bones—Common Sarcoma Sites
Leg bones
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Causes

The causes of Ewing's sarcoma are not fully understood. Chromosomal rearrangement that alters the genes may be a factor.

Risk Factors

Because the causes of the cancer are unknown, risk factors are also not fully understood. The following factors may increase your chance of developing Ewing's sarcoma:
  • Race: Caucasians
  • Age—Teenagers
  • Gender—Male

Symptoms

Symptoms include:
  • Pain, redness, and swelling surrounding the tumor
  • Fever
  • Weight loss and reduced appetite
  • Fatigue
  • Paralysis and incontinence in cases where the tumor is near the spinal cord
  • Numbness, tingling, and paralysis caused by compression of nerves by the tumor
  • Difficulty breathing if the tumor is in the chest wall

Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done. You will be treated by a team of doctors which may include an oncologist who specializes in cancer, an orthopaedic surgeon who operates on bones, and a radiation oncologist who works with radiation to kill cancer cells.Your bodily structures may need to be viewed. This can be done with:Your bodily fluids and tissues may need to be tested. This can be done with:
Bone Biopsy
Bone biopsy
Copyright © Nucleus Medical Media, Inc.

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