Cartilage

Supplement Forms / Alternate Names :

  • Bovine Cartilage
  • Shark Cartilage

Uses

Principal Proposed Uses

  • None

Other Proposed Uses

Cartilage is a tough connective tissue found in many parts of the body. Your ears and nose are made from cartilage, and so is the gliding surface in your joints. One constituent of cartilage, chondroitin , is widely used in Europe to treat osteoarthritis. Cartilage itself has also been proposed as a treatment for osteoarthritis. The most commonly used forms of cartilage come from cows (bovine cartilage) and sharks. Provocative evidence had suggested that shark cartilage might have some value in the treatment of cancer. However, properly designed studies have so far failed to find benefit.

Sources

Unless your uncle works at a slaughterhouse or you're brave enough to prepare your own cartilage from whole sharks, the preferred source of cartilage is your healthfood store or pharmacy, where you can purchase this supplement in pill or powdered form.

Therapeutic Dosages

Various doses of cartilage have been used in different studies, ranging from 2.5 mg to 60 g daily.

Therapeutic Uses

Based on the belief that sharks don't get cancer, shark cartilage has been heavily marketed as a cure for cancer . While this justification is a myth (sharks do get cancer), shark cartilage has, in fact, shown some promise for cancer treatment. Shark cartilage (like other forms of cartilage) contains substances that tend to inhibit angiogenesis (the growth of new blood vessels). Since cancers must build new blood vessels to feed themselves, this effect might be beneficial. Double-blind, placebo-controlled studies on special formulations of shark cartilage for the treatment of cancer are now underway. It has also been suggested that the anti-angiogenic properties of shark cartilage may make it helpful for psoriasis , but this hypothesis has not yet undergone proper study. 2 Shark cartilage also inhibits substances called matrix metalloproteases (MMPs). 1 These little-understood enzymes affect the "extracellular matrix," the framework of substances that lie between cells in the body. MMPs are thought to play a role in diseases of the cornea, gums, skin, blood vessels, and joints, as well as cancer and illnesses that involve excessive fibrous tissue. On this basis, shark cartilage has been proposed for a wide variety of medical conditions, from cataracts to scleroderma ; however, there are no meaningful studies as yet that can tell us whether it offers any benefit. Cartilage in general has been proposed as a treatment for the common "wear and tear" type of arthritis known as osteoarthritis . The idea behind this is straightforward: Because osteoarthritis is a disease of the joints, and because cartilage is one of the elements that make up your joints, adding cartilage to the diet might help. This idea sounds a bit too simplistic to be believable, but it is the same principle behind the use of glucosamine and chondroitin (specific substances found in the joints) for osteoarthritis. Since well designed studies have found those treatments effective, perhaps cartilage itself will ultimately be proven to work. However, such studies of cartilage have not yet been performed. Finally, highly preliminary studies hint that cartilage may help heal minor wounds . 3

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