Corticosteroids

Alternate Names :

  • Glucocorticoids

Calcium and Vitamin D —Helpful Interactions Aloe and Licorice (Topical) —Possible Supportive Interactions With Topical Steroids Creatine —Possible Helpful Interaction DHEA (Dehydroepiandrosterone) —Possible Helpful Interaction Chromium —Supplementation Possibly Helpful Ipriflavone —Possible Harmful Interaction Licorice (Internal) —Possible Harmful Interaction

Corticosteroid drugs (also known as glucocorticoids) act like the naturally occurring adrenal hormone cortisone in the body. They are strong anti-inflammatory and immune-suppressant medications used in many inflammatory and autoimmune conditions, such as rheumatoid arthritis , asthma , inflammatory bowel disease , and systemic lupus erythematosus . Corticosteroids are also prescribed to suppress transplant rejection. Drugs in this family include:

  • Betamethasone (Celestone)
  • Cortisone acetate (Cortone Acetate)
  • Dexamethasone (Decadron, Dexameth, Dexone, Hexadrol)
  • Hydrocortisone (Cortef, Hydrocortone)
  • Methylprednisolone (Medrol)
  • Prednisolone (Delta-Cortef, Pediapred, Prelone)
  • Prednisone (Deltasone, Liquid Pred, Meticorten, Orasone, Panasol-S, Prednicen-M, Sterapred DS)
  • Triamcinolone (Aristocort, Atolone, Kenacort)
  • And others

CalciumVitamin DOne of the most serious side effects of long-term corticosteroid use is accelerated osteoporosis. Although we don't fully understand how this works, corticosteroid interference with calcium and vitamin D is known to play a major role. Calcium and vitamin D supplements are definitely beneficial for fighting ordinary osteoporosis ; in addition, there is good evidence that they also protect against osteoporosis brought on by corticosteroids. 1 A review of 5 trials enrolling a total of 274 participants found that calcium and vitamin D supplementation significantly prevented bone loss at the lumbar spine and forearm in corticosteroid-treated individuals. 2 For example, in a 2-year double-blind placebo-controlled study of 130 individuals, supplementation with 1,000 mg of calcium and 500 IU of vitamin D daily actually reversed steroid-induced bone loss, causing a net bone gain. 3

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