Prosthetic Heart Valve Thrombosis

(Prosthetic Valve Thrombosis; PVT)


Prosthetic heart valve thrombosis is a rare, but serious complication of a heart valve replacement procedure. The complication occurs when a blood clot called a thrombus is attached to or near a prosthetic heart valve. This can obstruct blood flow or interfere with the function of the valve.Prosthetic heart valve thrombosis is a medical emergency.Heart Valves With Prosthetic Replacements
BP00039 97870 1 heart valve.jpg
Copyright © Nucleus Medical Media, Inc.


Prosthetic heart valve thrombosis is thought to result from an interaction between components of blood and the prosthesis or blood flow in and around the prosthesis.

Risk Factors

Factors that may increase your chance of prosthetic heart valve thrombosis include:
  • Inadequate anticoagulant/blood thinning therapy after a valve transplant
  • Prosthesis located at the mitral valve in the heart
  • Atrial fibrillation
  • Medications, such as contraceptives
  • Cancerous tumors
  • Systemic diseases such as systemic lupus erythematosus, or inflammation and damage to various body tissues, including joints, skin, kidneys, heart, lungs, blood vessels, and brain
  • Reduced cardiac pumping—possibly from heart failure


Prosthetic heart valve thrombosis may cause:
  • Shortness of breath
  • Difficulty breathing while lying down
  • Swelling
  • Fatigue
  • Difficulty exercising
  • Chest pain, burning, or pressure
  • Nausea
  • Numbness
  • Loss of consciousness


Your doctor will ask about your symptoms and medical history. A physical exam may be done. Images evaluate your heart and surrounding structures. These may include:Your bodily fluids may need to be tested. This can be done with blood tests.

leave comments
Did you like this? Share with your family and friends.
Related Topics:
Current Research From Top Journals

Music May Improve Sleep Quality in Adults with Insomnia
October 2015

Insomnia can make your days miserable and a cure can be hard to find. There are some medications but there is some worry with side effects and the potential for addiction. Music is side effect free and according to this study may help you find sleep.

dot separator
previous editions

CPAP May Help Older Adults with Obstructive Sleep Apnea
September 2015

Water Before Meals May Promote Weight Loss
August 2015

Fecal Transplants Induce Ulcerative Colitis Remission
July 2015

dashed separator


Our Free Newsletter
click here to see all of our uplifting newsletters »