Acute Interstitial Nephritis

Definition

Acute interstitial nephritis is a kidney disorder that happens when the kidneys are unable to filter waste and fluid properly due to inflammation of the kidney.
Anatomy of the Kidney
Glomerulonephritis
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Causes

Acute interstitial nephritis can be caused by:
  • Certain medications
    • Antibiotics
    • Anti-ulcer drugs
    • Nonsteroidal anti-inflammatory drugs
    • Diuretics
  • Infections such as:
  • Conditions that affect the immune system such as lupus

Risk Factors

Risk factors that increase your chance of developing acute interstitial nephritis include:
  • In adults: drug or medication use
  • In children: infection

Symptoms

Symptoms include:
  • Decrease in urine output
  • Blood in urine
  • Side or loin pain
  • Swelling of the body
  • Nausea and vomiting
  • Loss of appetite
  • Weakness
  • Aching joints
  • Fever
  • Rash

Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done. Tests may include:

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