Crohn's Disease

(CD; Regional Enteritis)


Crohn's disease is a severe, chronic inflammatory bowel disease. It causes inflammation, ulcers, and bleeding in the digestive tract. It usually affects the end portion of the small intestine called the ileum. However, any part of the digestive tract can be affected, from the mouth to the anus.
Small Intestine
nucleus factsheet image
Copyright © Nucleus Medical Media, Inc.


The cause of Crohn's disease is not known. Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, seem to run in some families. Some researchers think that it is due to a reaction to a virus or bacteria that causes the immune system to overreact and damage the intestines.

Risk Factors

People of Jewish heritage are more likely to get Crohn's disease. Your risk may also be increased if you have family members with inflammatory bowel disease or other autoimmune diseases.


Symptoms include:
  • Diarrhea
  • Abdominal cramps and pain
  • Rectal bleeding
  • Weight loss
  • Fatigue, weakness
  • Nausea
  • Fever
  • Mouth sores
  • Sores, abscesses in the anal area
  • Antibiotics
Complications of untreated Crohn's disease may lead to:
  • Fistulas—Abnormal connections between the intestine and other organs or tissues, such as the bladder, vagina, or skin
  • Intestinal obstruction
  • Liver disease
  • Bowel perforation
  • Bleeding
  • Kidney stones
  • Gallstones
  • Osteoporosis

leave comments
Did you like this? Share with your family and friends.
Related Topics:
Current Research From Top Journals

Water Before Meals May Promote Weight Loss
August 2015

A randomized trial found that drinking water before main meals led to higher weight loss than those who were asked to imagine a full stomach before main meals. Water preloading is believed to help create a feeling of fullness or satiety during the meal, which may help curb overeating.

dot separator
previous editions

Fecal Transplants Induce Ulcerative Colitis Remission
July 2015

Exercise Associated with Healthy Baby Weight
June 2015

Mindful Meditation May Reduce Symptoms and Complications of Insomnia
May 2015

dashed separator


Our Free Newsletter
click here to see all of our uplifting newsletters »