Soft Tissue Sarcoma

(Alveolar Soft Part Sarcoma; Angiosarcoma; Dermatofibrosarcoma Protuberans; Desmoid Sarcoma; Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Malignant Fibrous Histiocytoma; Lymphoma (lymphosarcoma); Malignant Peripheral Nerve Sheath Tumor; Rhabdomyosarcoma; Synovial Sarcoma)

Definition

Soft tissue sarcoma is a disease in which cancer cells are found in soft tissue in the body. Soft tissue includes muscles, tendons, connective tissue, fat, blood vessels, nerves, and joint tissue. There are many types of soft tissue sarcoma.

Causes

Cancer occurs when cells in the body divide without control or order. Eventually these uncontrolled cells form a growth or tumor. The term cancer refers to malignant growths. These growths can invade nearby tissues including the lymph nodes. Cancer that has invaded the lymph nodes can then spread to other parts of the body.It is not clear exactly what causes these problems in the cells, but is probably a combination of genetics and environment.
Cancer Growth
Cancer Cell Division
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Risk Factors

Factors that may increase your risk of soft tissue sarcoma include:
  • Exposure to certain types of chemicals, such as:
    • Chemicals in herbicides and wood preservatives
    • Polycyclic hydrocarbons
    • Dioxin
  • Exposure to radiation, including therapeutic, diagnostic, and accidental
  • History of angiosarcoma of the liver
  • Weak or poorly functioning immune system, including having an HIV infection
  • Certain inherited diseases, such as:

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