Needle Biopsy of the Lung and Pleura
(Transthoracic Needle Aspiration; Percutaneous Needle Aspiration)
DefinitionA needle biopsy of the lung or pleura is done to remove a sample of lung or pleural tissue, or fluid. Pleura is the lining of the lungs and chest wall. Once the tissue is removed, it will be examined in a lab.
|Female Torso with Respiratory System and Ribcage (Anterior View)|
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Reasons for ProcedureThis procedure is used to diagnose abnormal tissue in or around the lung. Possible reasons for abnormal tissue are:
- Noncancerous tumors
- Lung tissue scarring
- Other infections (eg, tuberculosis or histoplasmosis)
- Abnormal blood vessels in the lung
- As a consequence of certain systemic diseases (eg, rheumatoid arthritis , sarcoidosis , or Wegener’s granulomatosis )
Possible ComplicationsComplications are rare, but no procedure is completely free of risk. If you are planning to have a needle biopsy, your doctor will review a list of possible complications, which may include:
- Collapsed lung
- Damage to the liver or spleen
What to Expect
Prior to ProcedureYour doctor may order:
- A complete physical exam
- Blood tests
- Images of the chest and lungs maybe taken with
- Aspirin or other anti-inflammatory drugs
- Blood thinners, such as clopidogrel or warfarin
- You may receive a mild sedative about an hour before the procedure. It will help you relax.
- You may also have an injection of a local anesthetic. It will numb the area where the needle will be inserted.
Description of the ProcedureYour skin will be cleaned with an antiseptic solution. You will be in a seated position, leaning forward, with your arms resting on a table for support. You should remain as still as possible. An ultrasound or CT scan will be used to locate the exact area.A small cut will be made in your skin. Then, while you hold your breath, the biopsy needle will be inserted through the cut. The needle will be passed between your ribs until it reaches the lung or pleura. Your doctor then withdraws some cells through the biopsy needle. The needle will be withdrawn. Pressure will be put on the site of the incision. When the bleeding stops, a bandage will be applied.
How Long Will It Take?Between 30-60 minutes
How Much Will It Hurt?
- Before the procedure, when the local anesthetic is injected, you may feel a brief sting.
- During the procedure, when the needle is inserted, you will probably feel some pressure. If you are having a lung biopsy, you will feel a quick, sharp pain when the needle touches your lung.
Post-procedure CareAt the Care Center
- You will rest for several hours after the procedure. A nurse will check on you and monitor your recovery.
- A few hours after the procedure, a chest x-ray or other imaging technique may be done. This is done to make sure a lung has not collapsed and that there is no bleeding.
- If there are no complications after four hours, you may go home.
- Rest at home for a day or two.
- Avoid strenuous activities for one week.
- You may remove the bandage after a day or two.
- Ask your doctor about when it is safe to shower, bathe, or soak in water.
- Be sure to follow your doctor's instructions.
Call Your DoctorAfter arriving home, contact your doctor if any of the following occurs:
- Signs of infection, including fever and chills
- Redness, swelling, increasing pain, excessive bleeding, or any discharge from the incision site
- Pain that you cannot control with the medicines you have been given
- Cough, shortness of breath, or chest pain
- Coughing up blood
- Pain when taking a deep breath
- You feel your heart rate is fast
American Cancer Society
American Lung Association
Canadian Cancer Society
Canadian Lung Association
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6/3/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/ : Mills E, Eyawo O, Lockhart I, Kelly S, Wu P, Ebbert JO. Smoking cessation reduces postoperative complications: a systematic review and meta-analysis.Am J Med. 2011;124(2):144-154.e8.
- Reviewer: Michael Woods, MD
- Review Date: 02/2014
- Update Date: 03/15/2013