The investigators reported that:

· The papaya leaf extract prevented the growth of breast cancer cells in culture with higher doses having a greater benefit.

· Prevention of cell growth appears to be mediated, at least in part, by stimulating the programmed cell death of the breast cancer cells.

· The papaya leaf extract suppressed the production on inflammatory chemicals from the white blood cells.

· Production of chemicals with possible anti-cancer properties were increased when white blood cells were treated with the papaya leaf extract. · None of the doses of the papaya leaf extract appeared to have any damaging effects normal cells.